hemE protein (Sphingobium sp. YBL2) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

hemE

Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (353 aa)

Predicted Functional Partners:

hemC

0.986

AJR22784.1

0.977

AJR26259.1

0.959

AJR22624.1

0.953

AJR24962.1

0.953

AJR24042.1

0.942

hemH

0.931

AJR23137.1

0.922

AJR22613.1

0.914

AJR25689.1

0.859

Your Current Organism:

Sphingobium sp. YBL2

NCBI taxonomy Id: 484429
Other names: S. sp. YBL2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJR22613.1	AJR22624.1	TZ53_01235	TZ53_01305	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
AJR22613.1	AJR24042.1	TZ53_01235	TZ53_10225	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.920
AJR22613.1	AJR24962.1	TZ53_01235	TZ53_15745	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
AJR22613.1	AJR25689.1	TZ53_01235	TZ53_20035	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.	0.860
AJR22613.1	hemC	TZ53_01235	TZ53_10230	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.	0.981
AJR22613.1	hemE	TZ53_01235	TZ53_04510	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.914
AJR22624.1	AJR22613.1	TZ53_01305	TZ53_01235	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.979
AJR22624.1	AJR24042.1	TZ53_01305	TZ53_10225	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.965
AJR22624.1	AJR24962.1	TZ53_01305	TZ53_15745	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AJR22624.1	AJR25689.1	TZ53_01305	TZ53_20035	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.	0.788
AJR22624.1	AJR26259.1	TZ53_01305	TZ53_07890	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.423
AJR22624.1	hemC	TZ53_01305	TZ53_10230	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.	0.840
AJR22624.1	hemE	TZ53_01305	TZ53_04510	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.953
AJR22624.1	hemH	TZ53_01305	TZ53_13735	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.631
AJR22784.1	AJR23137.1	TZ53_02365	TZ53_04505	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
AJR22784.1	AJR24042.1	TZ53_02365	TZ53_10225	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.402
AJR22784.1	AJR25689.1	TZ53_02365	TZ53_20035	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.	0.685
AJR22784.1	AJR26259.1	TZ53_02365	TZ53_07890	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.941
AJR22784.1	hemC	TZ53_02365	TZ53_10230	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.	0.678
AJR22784.1	hemE	TZ53_02365	TZ53_04510	Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.977