Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJR23243.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)    
Predicted Functional Partners:
AJR25619.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.811
AJR23244.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
  
  
 0.789
AJR24688.1
Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.740
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
  
 0.740
AJR24860.1
Citrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.633
AJR22884.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.628
AJR22479.1
citryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.577
AJR26062.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.527
AJR24856.1
methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.483
AJR25514.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.483
Your Current Organism:
Sphingobium sp. YBL2
NCBI taxonomy Id: 484429
Other names: S. sp. YBL2
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