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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJR23526.1Toxin MazF; ChpA; endoribonuclease; toxin of the MazF-MazE (ChpA-ChpR) toxin-antitoxin system; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)    
Predicted Functional Partners:
AJR23527.1
PbsX family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
AJR23499.1
CopG family transcriptional regulator; Transcriptional regulator.
  
 
 0.927
AJR26133.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.886
AJR23525.1
Addiction module antitoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.715
AJR23380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.533
AJR23528.1
Addiction module antitoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.500
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.452
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.439
AJR22471.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.437
AJR22473.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.437
Your Current Organism:
Sphingobium sp. YBL2
NCBI taxonomy Id: 484429
Other names: S. sp. YBL2
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