| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJR26470.1 | AJR26471.1 | TZ53_17205 | TZ53_17210 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.556 |
| AJR26470.1 | glyA | TZ53_17205 | TZ53_17200 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.990 |
| AJR26470.1 | nrdR | TZ53_17205 | TZ53_17195 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.851 |
| AJR26471.1 | AJR26470.1 | TZ53_17210 | TZ53_17205 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.556 |
| AJR26471.1 | glyA | TZ53_17210 | TZ53_17200 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.543 |
| AJR26471.1 | nrdR | TZ53_17210 | TZ53_17195 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.544 |
| glyA | AJR26470.1 | TZ53_17200 | TZ53_17205 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.990 |
| glyA | AJR26471.1 | TZ53_17200 | TZ53_17210 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
| glyA | nrdR | TZ53_17200 | TZ53_17195 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.877 |
| nrdR | AJR26470.1 | TZ53_17195 | TZ53_17205 | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.851 |
| nrdR | AJR26471.1 | TZ53_17195 | TZ53_17210 | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.544 |
| nrdR | glyA | TZ53_17195 | TZ53_17200 | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.877 |