| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJR24134.1 | AJR26182.1 | TZ53_10740 | TZ53_05185 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. | 0.641 |
| AJR24134.1 | glsA | TZ53_10740 | TZ53_17305 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutaminase; Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. | 0.943 |
| AJR24134.1 | murD | TZ53_10740 | TZ53_00935 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.689 |
| AJR24134.1 | murI | TZ53_10740 | TZ53_19100 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.578 |
| AJR24134.1 | purQ | TZ53_10740 | TZ53_16425 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.902 |
| AJR24134.1 | topA | TZ53_10740 | TZ53_19085 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.838 |
| AJR25526.1 | AJR25528.1 | TZ53_19090 | TZ53_19105 | DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.539 |
| AJR25526.1 | murI | TZ53_19090 | TZ53_19100 | DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.696 |
| AJR25526.1 | plsY | TZ53_19090 | TZ53_19095 | DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.886 |
| AJR25526.1 | topA | TZ53_19090 | TZ53_19085 | DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.911 |
| AJR25528.1 | AJR25526.1 | TZ53_19105 | TZ53_19090 | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.539 |
| AJR25528.1 | murI | TZ53_19105 | TZ53_19100 | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.689 |
| AJR25528.1 | plsY | TZ53_19105 | TZ53_19095 | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.466 |
| AJR25528.1 | topA | TZ53_19105 | TZ53_19085 | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.570 |
| AJR26046.1 | AJR26182.1 | TZ53_22165 | TZ53_05185 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. | 0.533 |
| AJR26046.1 | murI | TZ53_22165 | TZ53_19100 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.903 |
| AJR26182.1 | AJR24134.1 | TZ53_05185 | TZ53_10740 | Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.641 |
| AJR26182.1 | AJR26046.1 | TZ53_05185 | TZ53_22165 | Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.533 |
| AJR26182.1 | murD | TZ53_05185 | TZ53_00935 | Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.983 |
| AJR26182.1 | murI | TZ53_05185 | TZ53_19100 | Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.563 |
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