Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
AJR25586.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)    
Predicted Functional Partners:
ychF
GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.780
AJR26520.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.668
AJR25587.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.629
AJR25584.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
AJR25588.1
Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.508
polA
DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.451
AJR22446.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.441
AJR23126.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.441
AJR23431.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.441
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.414
Your Current Organism:
Sphingobium sp. YBL2
NCBI taxonomy Id: 484429
Other names: S. sp. YBL2
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