MYSM1_1 protein (Rhizopus stolonifer) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

MYSM1_1

Myb-like, SWIRM and MPN domains 1. (299 aa)

Predicted Functional Partners:

CU098_007150

0.996

NEDD8

0.995

CU098_012679

0.995

CRP79

0.978

RPN9

0.976

CU098_008036

0.975

GCN5_2

0.975

GCN5_1

0.975

CU098_002514

0.975

SPT7_1

0.975

Your Current Organism:

Rhizopus stolonifer

NCBI taxonomy Id: 4846
Other names: Mucor stolonifer, R. stolonifer, Rhizopus nigricans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRP79	CU098_002514	A0A367J4J6	A0A367IVG7	Poly(A) binding protein Crp79.	Uncharacterized protein.	0.759
CRP79	CU098_007150	A0A367J4J6	A0A367IK23	Poly(A) binding protein Crp79.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.990
CRP79	CU098_008036	A0A367J4J6	A0A367IRR3	Poly(A) binding protein Crp79.	Uncharacterized protein.	0.759
CRP79	CU098_012679	A0A367J4J6	A0A367KM78	Poly(A) binding protein Crp79.	Ubiquitin-like domain-containing protein.	0.990
CRP79	GCN5_1	A0A367J4J6	A0A367IVC5	Poly(A) binding protein Crp79.	Histone acetyltransferase.	0.767
CRP79	GCN5_2	A0A367J4J6	A0A367ITK2	Poly(A) binding protein Crp79.	Histone acetyltransferase.	0.767
CRP79	MYSM1_1	A0A367J4J6	A0A367IJQ1	Poly(A) binding protein Crp79.	Myb-like, SWIRM and MPN domains 1.	0.978
CRP79	NEDD8	A0A367J4J6	A0A367KC46	Poly(A) binding protein Crp79.	Nedd8-conjugating enzyme UBE2F.	0.993
CRP79	RPN9	A0A367J4J6	A0A367KWJ0	Poly(A) binding protein Crp79.	26S proteasome regulatory subunit.	0.989
CRP79	SPT7_1	A0A367J4J6	A0A367K2G0	Poly(A) binding protein Crp79.	Transcriptional activator spt7.	0.796
CU098_002514	CRP79	A0A367IVG7	A0A367J4J6	Uncharacterized protein.	Poly(A) binding protein Crp79.	0.759
CU098_002514	CU098_007150	A0A367IVG7	A0A367IK23	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.754
CU098_002514	CU098_012679	A0A367IVG7	A0A367KM78	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.719
CU098_002514	MYSM1_1	A0A367IVG7	A0A367IJQ1	Uncharacterized protein.	Myb-like, SWIRM and MPN domains 1.	0.975
CU098_002514	NEDD8	A0A367IVG7	A0A367KC46	Uncharacterized protein.	Nedd8-conjugating enzyme UBE2F.	0.719
CU098_007150	CRP79	A0A367IK23	A0A367J4J6	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Poly(A) binding protein Crp79.	0.990
CU098_007150	CU098_002514	A0A367IK23	A0A367IVG7	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.754
CU098_007150	CU098_008036	A0A367IK23	A0A367IRR3	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.754
CU098_007150	CU098_012679	A0A367IK23	A0A367KM78	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Ubiquitin-like domain-containing protein.	0.979
CU098_007150	GCN5_1	A0A367IK23	A0A367IVC5	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Histone acetyltransferase.	0.754

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Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.777

expected number of edges:

11

PPI enrichment p-value:

2.54e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008616

Queuosine biosynthetic process

4 of 9

2.28

2.48

1.52e-05

GO:0006396

RNA processing

5 of 61

1.55

1.79

2.65e-05

GO:0008033

tRNA processing

4 of 37

1.67

1.69

0.00014

GO:0034654

Nucleobase-containing compound biosynthetic process

6 of 167

1.19

1.22

9.00e-05

GO:1901137

Carbohydrate derivative biosynthetic process

6 of 172

1.18

1.19

9.90e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140101

Catalytic activity, acting on a tRNA

4 of 57

1.48

0.99

0.0063

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1534

0.45

0.33

0.0142

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1459

Mixed, incl. Queuosine biosynthesis, and Ion transporter-like, CBS domain

5 of 21

2.01

2.73

1.62e-06

CL:1484

Queuosine biosynthesis, and Ribbon-helix-helix domain

3 of 5

2.41

1.98

0.00019

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0671

Queuosine biosynthesis

4 of 7

2.39

3.08

1.13e-06

KW-0819

tRNA processing

4 of 25

1.84

2.03

3.96e-05

KW-0963

Cytoplasm

5 of 252

0.93

0.62

0.0116

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