STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATG8_2Autophagy-related protein. (118 aa)    
Predicted Functional Partners:
CU098_003932
Uncharacterized protein.
   
 0.998
CU098_011926
Uncharacterized protein.
   
 0.998
ATG1
Serine/threonine-protein kinase.
   
 0.991
ATG4_2
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.
   
 0.987
ATG3_2
Autophagy-related protein 3.
  
 0.987
CU098_010104
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.
   
 0.987
ATG4_1
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.
   
 0.985
ATG3_1
E2-like enzyme.
   
 0.984
ATG7_2
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.984
ATG7_1
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.984
Your Current Organism:
Rhizopus stolonifer
NCBI taxonomy Id: 4846
Other names: Mucor stolonifer, R. stolonifer, Rhizopus nigricans
Server load: low (26%) [HD]