CU098_002841 protein (Rhizopus stolonifer) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

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gene co-occurrence

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protein homology

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Score

CU098_002841

Lipase_3 domain-containing protein. (556 aa)

Predicted Functional Partners:

TAF9

0.860

TAF10

0.859

CU098_012456

0.847

CU098_007486

0.846

CU098_009794

0.834

CU098_004257

0.833

TAF11

0.830

CU098_000453

0.829

TAF13

0.828

CU098_003446

0.826

Your Current Organism:

Rhizopus stolonifer

NCBI taxonomy Id: 4846
Other names: Mucor stolonifer, R. stolonifer, Rhizopus nigricans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CU098_000453	CU098_002841	A0A367KNI6	A0A367JU13	ANAPC4 domain-containing protein.	Lipase_3 domain-containing protein.	0.829
CU098_000453	CU098_004257	A0A367KNI6	A0A367IPM8	ANAPC4 domain-containing protein.	DOC domain-containing protein.	0.997
CU098_002841	CU098_000453	A0A367JU13	A0A367KNI6	Lipase_3 domain-containing protein.	ANAPC4 domain-containing protein.	0.829
CU098_002841	CU098_003446	A0A367JU13	A0A367IIW3	Lipase_3 domain-containing protein.	Uncharacterized protein.	0.826
CU098_002841	CU098_004257	A0A367JU13	A0A367IPM8	Lipase_3 domain-containing protein.	DOC domain-containing protein.	0.833
CU098_002841	CU098_007486	A0A367JU13	A0A367J4V8	Lipase_3 domain-containing protein.	Uncharacterized protein.	0.846
CU098_002841	CU098_009794	A0A367JU13	A0A367KU82	Lipase_3 domain-containing protein.	TAFII55_N domain-containing protein.	0.834
CU098_002841	CU098_012456	A0A367JU13	A0A367KLJ4	Lipase_3 domain-containing protein.	Uncharacterized protein.	0.847
CU098_002841	TAF10	A0A367JU13	A0A367JK54	Lipase_3 domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.859
CU098_002841	TAF11	A0A367JU13	A0A367J9D4	Lipase_3 domain-containing protein.	Transcription initiation factor TFIID subunit 11.	0.830
CU098_002841	TAF13	A0A367JU13	A0A367KUS4	Lipase_3 domain-containing protein.	Transcription initiation factor TFIID subunit 13.	0.828
CU098_002841	TAF9	A0A367JU13	A0A367KSQ6	Lipase_3 domain-containing protein.	Transcription initiation factor TFIID subunit 9.	0.860
CU098_003446	CU098_002841	A0A367IIW3	A0A367JU13	Uncharacterized protein.	Lipase_3 domain-containing protein.	0.826
CU098_003446	CU098_012456	A0A367IIW3	A0A367KLJ4	Uncharacterized protein.	Uncharacterized protein.	0.997
CU098_004257	CU098_000453	A0A367IPM8	A0A367KNI6	DOC domain-containing protein.	ANAPC4 domain-containing protein.	0.997
CU098_004257	CU098_002841	A0A367IPM8	A0A367JU13	DOC domain-containing protein.	Lipase_3 domain-containing protein.	0.833
CU098_007486	CU098_002841	A0A367J4V8	A0A367JU13	Uncharacterized protein.	Lipase_3 domain-containing protein.	0.846
CU098_009794	CU098_002841	A0A367KU82	A0A367JU13	TAFII55_N domain-containing protein.	Lipase_3 domain-containing protein.	0.834
CU098_009794	TAF10	A0A367KU82	A0A367JK54	TAFII55_N domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.997
CU098_009794	TAF11	A0A367KU82	A0A367J9D4	TAFII55_N domain-containing protein.	Transcription initiation factor TFIID subunit 11.	0.998

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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