STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKA75287.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family. (269 aa)    
Predicted Functional Partners:
SKB00977.1
Acyl transferase domain-containing protein.
  
 0.920
SKA75952.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.843
SKA95144.1
SnoaL-like domain-containing protein.
 
  
  0.786
SKB03429.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.702
lpxC
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
 0.654
SKA86491.1
3-hydroxyacyl-[acyl-carrier-protein] dehydratase.
  
 0.644
SKA75283.1
Predicted lactoylglutathione lyase.
       0.628
SKB01254.1
Glycosyltransferase, GT2 family.
   
 
 0.623
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.591
SKA80559.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.562
Your Current Organism:
Prosthecobacter debontii
NCBI taxonomy Id: 48467
Other names: ATCC 700200, P. debontii, Prosthecobacter FC3, Prosthecobacter sp. FC-3, strain FC3
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