STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB02898.15-oxoprolinase (ATP-hydrolysing). (1225 aa)    
Predicted Functional Partners:
SKA75952.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.862
SKA77031.1
Gamma-glutamyltranspeptidase / glutathione hydrolase.
 
  
 0.850
SKB02032.1
Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.822
SKB01431.1
Urea carboxylase.
    
 0.817
glsA
L-glutaminase; Belongs to the glutaminase family.
    
 0.784
nuoI
NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
  0.779
SKA94557.1
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
    
  0.778
SKA97808.1
NADP-dependent aldehyde dehydrogenase.
   
 
  0.776
SKB00370.1
Acyl-CoA reductase.
   
 
  0.776
SKB02895.1
Protein of unknown function.
       0.762
Your Current Organism:
Prosthecobacter debontii
NCBI taxonomy Id: 48467
Other names: ATCC 700200, P. debontii, Prosthecobacter FC3, Prosthecobacter sp. FC-3, strain FC3
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