STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (297 aa)    
Predicted Functional Partners:
SKB00095.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.967
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.945
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
 
 0.900
SKA76864.1
Valine-pyruvate aminotransferase apoenzyme.
     
 0.883
SKB00977.1
Acyl transferase domain-containing protein.
  
 
 0.870
SKA76339.1
Chorismate mutase.
    
 0.844
SKA80331.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.806
SKA88212.1
Threonine dehydratase.
  
 
 0.800
SKA94425.1
Homoserine dehydrogenase.
  
 
 0.790
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.786
Your Current Organism:
Prosthecobacter debontii
NCBI taxonomy Id: 48467
Other names: ATCC 700200, P. debontii, Prosthecobacter FC3, Prosthecobacter sp. FC-3, strain FC3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.