STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UFO1_0545TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU), RNA 2-O ribose methyltransferase substrate binding protein; KEGG: rlmB, putative 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB; SMART: RNA 2-O ribose methyltransferase substrate binding protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (249 aa)    
Predicted Functional Partners:
UFO1_0547
PFAM: protein of unknown function DUF901; KEGG: hypothetical protein.
  
  
 0.935
UFO1_2084
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
 
 
 0.911
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.903
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.894
engB
GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
 
 
 0.887
mrnC
Putative conserved protein UCP005520; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
 
  
 0.872
mnmE
tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 
 0.849
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 
 0.840
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
 
 
 0.840
cysS
KEGG: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase/mycothiol ligase, Cysteinyl-tRNA synthetase class Ia DALR; TIGRFAM: cysteinyl-tRNA synthetase; HAMAP : Cysteinyl-tRNA synthetase; SMART: Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.833
Your Current Organism:
Pelosinus sp. UFO1
NCBI taxonomy Id: 484770
Other names: P. sp. UFO1, Pelosinus lilaceae
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