OLF09124.1 protein (Actinophytocola xinjiangensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

OLF09124.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (80 aa)

Predicted Functional Partners:

OLF09125.1

0.542

OLF09126.1

0.542

OLF09123.1

0.468

OLF09127.1

0.408

Your Current Organism:

Actinophytocola xinjiangensis

NCBI taxonomy Id: 485602
Other names: A. xinjiangensis, Actinophytocola sp. QAIII60, Actinophytocola xinjiangensis Guo et al. 2011, Amycolatopsis sp. QAIII60, CGMCC 4.4663, DSM 45854, NBRC 106673, strain QAIII60

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OLF09123.1	OLF09124.1	BLA60_21350	BLA60_21355	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.468
OLF09123.1	OLF09125.1	BLA60_21350	BLA60_21360	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.501
OLF09124.1	OLF09123.1	BLA60_21355	BLA60_21350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
OLF09124.1	OLF09125.1	BLA60_21355	BLA60_21360	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
OLF09124.1	OLF09126.1	BLA60_21355	BLA60_21365	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
OLF09124.1	OLF09127.1	BLA60_21355	BLA60_21370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.408
OLF09125.1	OLF09123.1	BLA60_21360	BLA60_21350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.501
OLF09125.1	OLF09124.1	BLA60_21360	BLA60_21355	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.542
OLF09125.1	OLF09126.1	BLA60_21360	BLA60_21365	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
OLF09125.1	OLF09127.1	BLA60_21360	BLA60_21370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.563
OLF09126.1	OLF09124.1	BLA60_21365	BLA60_21355	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.542
OLF09126.1	OLF09125.1	BLA60_21365	BLA60_21360	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
OLF09126.1	OLF09127.1	BLA60_21365	BLA60_21370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.563
OLF09127.1	OLF09124.1	BLA60_21370	BLA60_21355	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.408
OLF09127.1	OLF09125.1	BLA60_21370	BLA60_21360	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.563
OLF09127.1	OLF09126.1	BLA60_21370	BLA60_21365	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.563

Network Stats

number of nodes:

11

number of edges:

10

average node degree:

1.82

avg. local clustering coefficient:

0.909

expected number of edges:

11

PPI enrichment p-value:

0.625

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030001

Metal ion transport

6 of 44

1.63

2.28

1.10e-06

GO:0006812

Cation transport

7 of 72

1.48

2.05

8.58e-07

GO:0098662

Inorganic cation transmembrane transport

5 of 36

1.64

2.01

1.12e-05

GO:0006811

Ion transport

8 of 136

1.26

1.63

8.58e-07

GO:0055085

Transmembrane transport

8 of 276

0.96

3.14e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005388

P-type calcium transporter activity

4 of 4

2.49

3.1

1.27e-06

GO:0046873

Metal ion transmembrane transporter activity

5 of 20

1.89

2.64

1.27e-06

GO:0022853

Active ion transmembrane transporter activity

5 of 31

1.7

2.27

2.97e-06

GO:0008324

Cation transmembrane transporter activity

6 of 50

1.57

2.17

1.27e-06

GO:0022804

Active transmembrane transporter activity

7 of 79

1.44

1.96

9.33e-07

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

10 of 1019

0.49

0.37

0.0046

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5719

Mixed, incl. Cation/H+ exchanger, and Calcium ion transport

5 of 12

2.11

3.17

2.39e-07

CL:5717

Mixed, incl. Cation/H+ exchanger, and Calcium ion transport

6 of 23

1.91

3.1

7.05e-08

CL:5721

Cation transport ATPase (P-type), and Cation/H+ exchanger

4 of 5

2.4

3.09

1.08e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

4 of 44

1.45

1.22

0.0012

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005887

Integral component of plasma membrane

6 of 34

1.74

2.66

2.21e-07

GOCC:0016021

Integral component of membrane

7 of 121

1.26

1.55

2.43e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1133

Transmembrane helix

9 of 702

0.6

0.45

0.0048

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00689

Cation transporting ATPase, C-terminus

4 of 4

2.49

2.99

2.15e-06

PF00122

E1-E2 ATPase

4 of 6

2.32

2.82

3.21e-06

PF13246

Cation transport ATPase (P-type)

3 of 3

2.49

2.17

8.81e-05

PF00999

Sodium/hydrogen exchanger family

2 of 6

2.02

0.78

0.0352

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006068

Cation-transporting P-type ATPase, C-terminal

4 of 4

2.49

2.79

5.30e-06

IPR044492

P-type ATPase, haloacid dehalogenase domain

4 of 5

2.4

2.75

5.30e-06

IPR023299

P-type ATPase, cytoplasmic domain N

4 of 6

2.32

2.72

5.30e-06

IPR023298

P-type ATPase, transmembrane domain superfamily

4 of 6

2.32

2.72

5.30e-06

IPR018303

P-type ATPase, phosphorylation site

4 of 6

2.32

2.72

5.30e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00831

Cation transporter/ATPase, N-terminus

3 of 3

2.49

2.29

5.11e-05

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