OLF08524.1 protein (Actinophytocola xinjiangensis)

Nodes:

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second shell of interactors

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Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OLF08524.1

Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)

Predicted Functional Partners:

OLF10976.1

0.983

OLF08412.1

0.980

OLF08398.1

0.948

OLF08413.1

0.904

OLF11007.1

0.891

OLF10112.1

0.884

OLF11004.1

0.880

OLF04313.1

0.869

OLF10024.1

0.868

OLF08442.1

0.868

Your Current Organism:

Actinophytocola xinjiangensis

NCBI taxonomy Id: 485602
Other names: A. xinjiangensis, Actinophytocola sp. QAIII60, Actinophytocola xinjiangensis Guo et al. 2011, Amycolatopsis sp. QAIII60, CGMCC 4.4663, DSM 45854, NBRC 106673, strain QAIII60

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OLF04313.1	OLF08398.1	BLA60_41460	BLA60_23565	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLF04313.1	OLF08412.1	BLA60_41460	BLA60_23655	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
OLF04313.1	OLF08413.1	BLA60_41460	BLA60_23660	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.965
OLF04313.1	OLF08442.1	BLA60_41460	BLA60_23825	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLF04313.1	OLF08524.1	BLA60_41460	BLA60_23650	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.869
OLF04313.1	OLF10024.1	BLA60_41460	BLA60_16300	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	Translation initiation factor IF-3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
OLF04313.1	OLF10112.1	BLA60_41460	BLA60_16790	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
OLF04313.1	OLF10976.1	BLA60_41460	BLA60_13205	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLF04313.1	OLF11004.1	BLA60_41460	BLA60_13360	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L10; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLF04313.1	OLF11007.1	BLA60_41460	BLA60_13380	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLF08398.1	OLF04313.1	BLA60_23565	BLA60_41460	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLF08398.1	OLF08412.1	BLA60_23565	BLA60_23655	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
OLF08398.1	OLF08413.1	BLA60_23565	BLA60_23660	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.941
OLF08398.1	OLF08442.1	BLA60_23565	BLA60_23825	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
OLF08398.1	OLF08524.1	BLA60_23565	BLA60_23650	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
OLF08398.1	OLF10024.1	BLA60_23565	BLA60_16300	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	Translation initiation factor IF-3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.705
OLF08398.1	OLF10112.1	BLA60_23565	BLA60_16790	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.986
OLF08398.1	OLF10976.1	BLA60_23565	BLA60_13205	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
OLF08398.1	OLF11004.1	BLA60_23565	BLA60_13360	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L10; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
OLF08398.1	OLF11007.1	BLA60_23565	BLA60_13380	50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

22

PPI enrichment p-value:

2.99e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044255

Cellular lipid metabolic process

11 of 444

1.26

2.05

2.20e-11

GO:0006631

Fatty acid metabolic process

9 of 342

1.29

1.89

1.18e-08

GO:0044248

Cellular catabolic process

9 of 377

1.25

1.77

2.08e-08

GO:0010142

Farnesyl diphosphate biosynthetic process, mevalonate pathway

2 of 2

2.87

1.63

0.0011

GO:1901575

Organic substance catabolic process

9 of 517

1.11

1.38

2.23e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070403

NAD+ binding

8 of 9

2.82

8.8

7.61e-18

GO:0016616

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

8 of 74

1.9

4.35

3.64e-12

GO:0004421

hydroxymethylglutaryl-CoA synthase activity

2 of 2

2.87

1.56

0.0015

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 2275

0.51

0.39

0.0038

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1105

Butanoate metabolism, and Thiolase, C-terminal domain

9 of 43

2.19

6.53

2.78e-16

CL:1108

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, and Limonene and pinene degradation

7 of 24

2.33

5.9

2.52e-13

CL:1098

Mixed, incl. Fatty acid degradation, and Butanoate metabolism

10 of 93

1.9

5.29

2.78e-16

CL:1109

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, and Limonene and pinene degradation

6 of 19

2.37

5.16

2.40e-11

CL:1111

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, and Thiolase, C-terminal domain

5 of 13

2.45

4.47

1.48e-09

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00650

Butanoate metabolism

9 of 66

2.0

5.54

2.26e-15

map00362

Benzoate degradation

8 of 107

1.74

3.68

1.42e-11

map00360

Phenylalanine metabolism

6 of 79

1.75

2.95

2.30e-08

map01200

Carbon metabolism

7 of 211

1.39

2.02

9.70e-08

map00280

Valine, leucine and isoleucine degradation

4 of 89

1.52

1.58

0.00012

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070062

Extracellular exosome

7 of 15

2.54

6.64

3.92e-14

GOCC:0065010

Extracellular membrane-bounded organelle

7 of 23

2.35

5.95

2.33e-13

GOCC:0043227

Membrane-bounded organelle

10 of 586

1.1

1.49

1.99e-09

GOCC:0005777

Peroxisome

3 of 129

1.24

0.75

0.0158

GOCC:0005829

Cytosol

7 of 830

0.79

0.66

0.00081

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0560

Oxidoreductase

8 of 720

0.91

0.85

0.00012

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00725

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

8 of 8

2.87

9.02

3.98e-18

PF02737

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain

4 of 6

2.69

3.62

1.69e-07

PF03446

NAD binding domain of 6-phosphogluconate dehydrogenase

4 of 12

2.39

3.11

9.74e-07

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