STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFCOGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterProIPR011995:IPR018089:IPR001754:IPR011060:IPR 013785; KEGG: azo:azo3659 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: A1KBR9 Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. (279 aa)    
Predicted Functional Partners:
pyrE-2
Phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.992
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.978
EFH88996.1
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082:IPR006132:IPR006131:IPR006130; KEGG: pab:PAB1498 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: D0N6Y5 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Bel [...]
 
  
 0.965
pyrE
Phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.963
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR006274:IPR002474:IPR000991:IPR017926:IPR 001317:IPR011702:IPR006220; KEGG: aps:CFPG_497 carbamoyl-phosphate synthase; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; SPTR: B6YRD8 Carbamoyl-phosphate synthase; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 
  
 0.959
EFH88994.1
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005479:IPR005481:IPR005480:IPR 011607:IPR004088:IPR011761:IPR016185:IPR013817:IPR013816:I PR005483; KEGG: bfr:BF2635 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Q64SZ4 Carbamyl phosphate synthetase; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP bindin [...]
 
  
 0.955
Krac_5374
Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR011059:IPR006680:IPR002195; KEGG: cyb:CYB_2522 dihydroorotase; PFAM: amidohydrolase; SPTR: Q2JIT9 Dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type.
 
  
 0.892
allB
Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
  
  
 0.866
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.831
Krac_8231
Arsenite-activated ATPase ArsA; COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: cag:Cagg_0908 arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; PRIAM: Arsenite-transporting ATPase; SPTR: B8G5W5 Arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA).
    
 
 0.808
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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