STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFH89271.1COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR013785:IPR002638:IPR004393; KEGG: sti:Sthe_2195 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: D1C6J4 Nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (280 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.998
EFH89272.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.998
Krac_2004
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.989
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.878
Krac_6827
Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR008136:IPR001453; KEGG: mta:Moth_0735 competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; SPTR: Q2RKI6 Putative competence-damage inducible protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-ter [...]
    
 0.831
Krac_0189
Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; InterPro IPR004821:IPR014729:IPR016429; KEGG: mbt:JTY_0218 putative transcriptional regulatory protein; SPTR: Q7U2K1 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN NADR (PROBABLY ASNC-FAMILY); TIGRFAM: cytidyltransferase-related domain protein; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain.
     
 0.821
EFH89082.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
   
 0.812
Krac_3009
Hypothetical protein; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: A6G9I1 Putative uncharacterized protein.
     
 0.807
Krac_6794
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002869:IPR009014:IPR019752:IPR015941:IPR 002880; KEGG: chl:Chy400_1038 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: B9LLV4 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
    
  0.747
EFH90130.1
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086:IPR015797; KEGG: rrs:RoseRS_0145 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: A5UPN0 NUDIX hydrolase; PFAM: NUDIX domain.
 
    0.730
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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