STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFH89539.1NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR016040:IPR001509; KEGG: mxa:MXAN_0533 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Q099E2 Isoflavone reductase; PFAM: NAD dependent epimerase/dehydratase family. (336 aa)    
Predicted Functional Partners:
Krac_6972
Amino acid adenylation domain protein; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR009081:IPR006162:IPR020845:IPR 001242:IPR000873:IPR006163:IPR001031; KEGG: ava:Ava_1611 amino acid adenylation; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Thioesterase; SPTR: Q3MCQ2 Amino acid adenylation; TIGRFAM: amino acid adenylation domain protein; PFAM: Thioesterase domain; Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain.
  
 0.852
EFH90118.1
COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR016038:IPR001227:IPR000873:IPR006163:IPR 014030:IPR014031:IPR014043:IPR016039:IPR016035:IPR009081:I PR016036:IPR006162:IPR020845:IPR018201; KEGG: ava:Ava_4108 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; AMP-dependent synthetase and ligase; phosphopantetheine-binding; Acyl transferase; SPTR: Q3M5M8 Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain.
  
 0.840
EFH89515.1
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterProIPR011004:IPR016055:IPR017441:IPR005835:IPR 001451:IPR005844:IPR005845; KEGG: cag:Cagg_3774 nucleotidyl transferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: B8GB10 Nucleotidyl transferase; P [...]
  
 0.813
EFH90138.1
COGs: COG0069 Glutamate synthase domain 2; InterProIPR013785:IPR000583:IPR006982:IPR002932:IPR 002489:IPR017932; KEGG: tro:trd_1105 glutamate synthase [nadph] large chain precursor; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: B9L0N4 Glutamate synthase [nadph] large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
  0.751
EFH88919.1
Amino acid adenylation domain protein; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR006162:IPR020845:IPR001242:IPR 000873:IPR006163:IPR009081:IPR020459; KEGG: npu:Npun_F2181 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; SPTR: Q9RAH1 NosD; TIGRFAM: amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain.
  
 
 0.734
Krac_2411
Thioesterase; COGs: COG3319 Thioesterase domains of type I polyketide synthase or non-ribosomal peptide synthetase; InterPro IPR001031; KEGG: ara:Arad_7635 non-ribosomal peptide synthetase; PFAM: Thioesterase; SPTR: B4CW24 Amino acid adenylation domain protein; PFAM: Thioesterase domain.
    
 0.656
Krac_6794
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002869:IPR009014:IPR019752:IPR015941:IPR 002880; KEGG: chl:Chy400_1038 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: B9LLV4 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
    
  0.649
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.643
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
  0.641
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.640
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.