STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFH90271.12-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterProIPR016142:IPR002020:IPR016141:IPR011278:IPR 019810; KEGG: aac:Aaci_2221 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B7DSK4 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. (372 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.977
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.975
Krac_4356
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.973
Krac_7988
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.972
Krac_2456
Aconitate hydratase; COGs: COG1048 Aconitase A; InterProIPR015931:IPR015932:IPR015928:IPR006250:IPR 001030:IPR000573; KEGG: rxy:Rxyl_2824 aconitate hydratase; PFAM: aconitate hydratase domain protein; SPTR: Q1AS92 Aconitase; TIGRFAM: aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type.
 
 0.924
Krac_8733
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR012675:IPR012285:IPR009051:IPR001041:IPR 004489:IPR017896:IPR017900; KEGG: sti:Sthe_0996 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; PRIAM: Succinate dehydrogenase; SPTR: D1C2G5 Succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.919
EFH90570.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR016040:IPR008927:IPR013328:IPR006176:IPR 006108:IPR001753; KEGG: chy:CHY_1609 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; SPTR: Q3ABP7 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.885
EFH90118.1
COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR016038:IPR001227:IPR000873:IPR006163:IPR 014030:IPR014031:IPR014043:IPR016039:IPR016035:IPR009081:I PR016036:IPR006162:IPR020845:IPR018201; KEGG: ava:Ava_4108 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; AMP-dependent synthetase and ligase; phosphopantetheine-binding; Acyl transferase; SPTR: Q3M5M8 Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain.
  
 0.876
EFH90335.1
COGs: COG2225 Malate synthase; InterPro IPR011076:IPR015813:IPR019830:IPR006252; KEGG: aac:Aaci_2530 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: C8WT20 Malate synthase A; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
   
 0.864
Krac_2451
2-methylcitrate dehydratase; COGs: COG2079 Uncharacterized protein involved in propionate catabolism; InterPro IPR005656; KEGG: rxy:Rxyl_2564 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; PRIAM: 2-methylcitrate dehydratase; SPTR: B9XMR4 MmgE/PrpD family protein; PFAM: MmgE/PrpD family.
 
 
 0.864
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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