STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFH90445.1COGs: COG0515 Serine/threonine protein kinase; InterProIPR011009:IPR019734:IPR000719:IPR013026:IPR 011990:IPR008271:IPR017442:IPR001440:IPR013105:IPR020635:I PR002290; KEGG: cyc:PCC7424_1361 TPR repeat-containing protein; PFAM: Serine/threonine-protein kinase-like domain; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; Tetratricopeptide repeat; SPTR: B7K7N7 TPR repeat-containing protein; PFAM: Protein kinase domain; Tetratricopeptide repeat. (791 aa)    
Predicted Functional Partners:
Krac_7990
COGs: COG1716 FOG: FHA domain; InterPro IPR008984:IPR000253; KEGG: acp:A2cp1_3479 sigma54 specific transcriptional regulator, Fis family; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: B8J5E7 Sigma54 specific transcriptional regulator, Fis family; PFAM: FHA domain.
 
 0.853
EFH88736.1
Signal transduction histidine kinase with CheB and CheR activity; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000673:IPR000780:IPR013656:IPR003661:IPR 003594:IPR005467:IPR009082:IPR002052; KEGG: ava:Ava_0314 signal transduction histidine kinase (STHK) with CheB and CheR activity; PFAM: ATP-binding region ATPase domain protein; CheB methylesterase; MCP methyltransferase CheR-type; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: MCP methyltransferase CheR-type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; [...]
  
 0.845
EFH88743.1
Signal transduction histidine kinase with CheB and CheR activity; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000673:IPR000780:IPR013656:IPR003661:IPR 003594:IPR005467:IPR009082; KEGG: ava:Ava_0314 signal transduction histidine kinase (STHK) with CheB and CheR activity; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CheB methylesterase; MCP methyltransferase CheR-type; PAS fold-4 domain protein; SMART: MCP methyltransferase CheR-type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Q3M [...]
  
 0.845
Krac_8832
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: mxa:MXAN_4640 sensor histidine kinase/response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q1D3G7 Sensor protein; PFAM: Response regulator receiver domain.
   
 0.828
Krac_9408
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789; KEGG: rmr:Rmar_0513 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: D0MEW5 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain.
   
 0.823
Krac_4829
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR009082:IPR005467:IPR000014:IPR 000700:IPR004358:IPR001610:IPR003661:IPR013656:IPR013655; KEGG: rlg:Rleg_6856 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: C8SDN7 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: [...]
   
 0.802
Krac_6285
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR001789:IPR 013655:IPR003661:IPR000014:IPR001610:IPR004358:IPR005467:I PR000700; KEGG: rlg:Rleg_6856 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; SPTR: C8SDN7 PAS/PAC sensor sign [...]
   
 0.802
Krac_6537
Putative PAS/PAC sensor protein; COGs: COG2202 FOG: PAS/PAC domain; InterProIPR000014:IPR000700:IPR013767:IPR013656:IPR 013655:IPR001610; KEGG: aca:ACP_0447 sensory box sensor histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: C8SDN7 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
   
 0.802
Krac_4527
PAS/PAC sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR005467:IPR000014:IPR000700:IPR003594:IPR 009082:IPR001610:IPR003661:IPR004358:IPR013767:IPR013655; KEGG: phe:Phep_3913 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: A6EDD2 Sensor protein; TIGRFAM: PAS sensor pr [...]
   
 0.796
Krac_6708
Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR000014:IPR003018:IPR013767; KEGG: ter:Tery_0400 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; PAS fold domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; PAS domain containing protein; SPTR: B9YFB3 Adenylate/guanylate cyclase with GAF and PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF [...]
 
 
 0.795
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.