STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFH90454.1Bifunctional deaminase-reductase domain protein; COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: bcq:BCQ_3012 pyrimidine reductase; PFAM: bifunctional deaminase-reductase domain protein; SPTR: B9IRF5 Pyrimidine Reductase; PFAM: RibD C-terminal domain. (181 aa)    
Predicted Functional Partners:
Krac_4856
Bifunctional deaminase-reductase domain protein; COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: mpl:Mpal_1101 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; SPTR: B8GH42 Riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain.
  
     0.715
Krac_7841
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726:IPR003171; KEGG: tro:trd_1049 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: B9L045 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
    
 0.667
Krac_7682
COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR015421:IPR001085:IPR015424; KEGG: sin:YN1551_1249 glycine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: C3NEW0 Serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase.
  
 
 0.649
EFH89634.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.620
Krac_2746
COGs: COG0262 Dihydrofolate reductase; KEGG: ttr:Tter_2861 bifunctional deaminase-reductase domain protein; SPTR: D1C974 Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
  
     0.549
Krac_6654
Bifunctional deaminase-reductase domain protein; COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: saq:Sare_2943 deaminase-reductase domain-containing protein; PFAM: bifunctional deaminase-reductase domain protein; SPTR: A8M796 Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
  
     0.471
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.