STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFH90546.15-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR011234:IPR002529; KEGG: hau:Haur_0490 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9AV63 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. (314 aa)    
Predicted Functional Partners:
Krac_3643
COGs: COG3508 Homogentisate 1 2-dioxygenase; InterPro IPR011051:IPR005708; KEGG: hau:Haur_2762 homogentisate 12-dioxygenase; PFAM: homogentisate 12-dioxygenase; SPTR: A9B1V8 Homogentisate 12-dioxygenase; PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase.
  
  
 0.813
EFH90335.1
COGs: COG2225 Malate synthase; InterPro IPR011076:IPR015813:IPR019830:IPR006252; KEGG: aac:Aaci_2530 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: C8WT20 Malate synthase A; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
  
 
 0.598
Krac_2149
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR013785:IPR003042:IPR006076:IPR001155; KEGG: scl:sce8661 oxidoreductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD dependent oxidoreductase; SPTR: A9G078 Probable oxidoreductase; PFAM: FAD binding domain; NADH:flavin oxidoreductase / NADH oxidase family.
  
 
 0.591
Krac_8073
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR016040; KEGG: tle:Tlet_1697 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: A8F7W7 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
 
  0.552
Krac_8733
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR012675:IPR012285:IPR009051:IPR001041:IPR 004489:IPR017896:IPR017900; KEGG: sti:Sthe_0996 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; PRIAM: Succinate dehydrogenase; SPTR: D1C2G5 Succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
  0.513
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.512
fumC-2
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.512
Krac_9337
Protein of unknown function DUF162; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterProIPR012285:IPR009051:IPR007087:IPR017900:IPR 003741:IPR004017:IPR017896; KEGG: ttr:Tter_2256 protein of unknown function DUF162; PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: D1CHD4 Putative uncharacterized protein; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: 2[4Fe-4S] protein, putative.
  
 
  0.504
Krac_2463
InterPro IPR003953; KEGG: hau:Haur_3453 succinate dehydrogenase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: A3KI93 Putative oxidoreductase; manually curated; PFAM: domain; FAD binding domain.
  
 
  0.503
Krac_8162
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155:IPR013785; KEGG: ank:AnaeK_3776 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: C4CVF6 NADH:flavin oxidoreductase; PFAM: NADH:flavin oxidoreductase / NADH oxidase family.
    
 0.503
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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