Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Krac_3203RNA-directed DNA polymerase (Reverse transcriptase); COGs: COG3344 Retron-type reverse transcriptase; InterPro IPR000477:IPR013597:IPR002711:IPR003615; KEGG: mar:MAE_48790 RNA-directed DNA polymerase; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; HNH endonuclease; SMART: HNH nuclease; SPTR: A0YZ78 Putative uncharacterized protein; PFAM: HNH endonuclease; Group II intron, maturase-specific domain; Reverse transcriptase (RNA-dependent DNA polymerase). (598 aa)    
Predicted Functional Partners:
Krac_6887
KEGG: bpt:Bpet4285 mobile mitochondrial group II intron of COX1 which IS involved in pre-mRNA splicing and in deletion of introns from mitochondrial DNA; SPTR: A9IAV6 Mobile mitochondrial group II intron of COX1 which is involved in pre-mRNA splicing and in deletion of introns from mitochondrial DNA.
  
     0.700
EFH89634.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.554
Krac_7841
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726:IPR003171; KEGG: tro:trd_1049 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: B9L045 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
     
  0.554
Krac_7682
COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR015421:IPR001085:IPR015424; KEGG: sin:YN1551_1249 glycine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: C3NEW0 Serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase.
     
  0.520
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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