STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (380 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 0.964
EFH90138.1
COGs: COG0069 Glutamate synthase domain 2; InterProIPR013785:IPR000583:IPR006982:IPR002932:IPR 002489:IPR017932; KEGG: tro:trd_1105 glutamate synthase [nadph] large chain precursor; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: B9L0N4 Glutamate synthase [nadph] large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
 
  
 0.816
Krac_8583
COGs: COG0506 Proline dehydrogenase; InterPro IPR008219:IPR002872; KEGG: ttr:Tter_0599 proline dehydrogenase; PFAM: Proline dehydrogenase; SPTR: D1C8A2 Proline dehydrogenase; PFAM: Proline dehydrogenase.
    
 0.715
Krac_7969
Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814:IPR015424:IPR015421; KEGG: dba:Dbac_2006 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: C7LNC4 Aminotransferase class-III; PFAM: Aminotransferase class-III; TIGRFAM: putrescine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.647
EFH90629.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR016162:IPR016160:IPR015590; KEGG: sti:Sthe_0805 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: D1C1X5 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family.
     
 0.646
Krac_4321
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR010061:IPR015590:IPR016162:IPR016160:IPR 016161; KEGG: aba:Acid345_1533 methylmalonate-semialdehyde dehydrogenase [acylating]; PFAM: Aldehyde Dehydrogenase; SPTR: B4VJJ9 Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
     
 0.646
Krac_7757
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR016160:IPR016161:IPR015590:IPR005932:IPR 016162; KEGG: hau:Haur_4731 putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: A9B212 Putative delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative.
     
 0.646
Krac_8929
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016162:IPR016161:IPR016160:IPR015590; KEGG: sti:Sthe_0805 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: D1C1X5 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family.
     
 0.646
Krac_8350
COGs: COG0423 Glycyl-tRNA synthetase (class II); InterPro IPR002314:IPR004154:IPR006195:IPR002315; KEGG: tde:TDE0020 glycyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; SPTR: Q73RR5 Glycyl-tRNA synthetase; TIGRFAM: glycyl-tRNA synthetase; manually curated; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: glycyl-tRNA synthetase, dimeric type.
 
 
    0.640
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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