STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krac_3304NUDIX hydrolase; COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086:IPR015797; KEGG: eat:EAT1b_1555 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: C4KZG8 NUDIX hydrolase; manually curated; PFAM: NUDIX domain. (258 aa)    
Predicted Functional Partners:
Krac_8230
COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060:IPR008949:IPR019845; KEGG: plt:Plut_1356 phytoene desaturase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Q3B366 Phytoene desaturase; PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnD.
  
 
 0.698
Krac_7841
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726:IPR003171; KEGG: tro:trd_1049 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: B9L045 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
  
  
 0.604
Krac_7777
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
 
 0.597
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.569
Krac_7544
Trans-hexaprenyltranstransferase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR008949:IPR000092; KEGG: drm:Dred_2166 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: A4J6I0 Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.553
Krac_7668
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR008949:IPR000092; KEGG: hau:Haur_4493 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: A9AZS1 Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.553
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
     
 0.543
Krac_2784
MOSC domain containing protein; COGs: COG2258 conserved hypothetical protein; InterPro IPR011037:IPR005302:IPR015808; KEGG: npu:Npun_F2216 MOSC domain-containing protein; PFAM: MOSC domain containing protein; SPTR: B2J6B2 MOSC domain containing protein; PFAM: MOSC domain.
  
     0.421
Krac_2149
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR013785:IPR003042:IPR006076:IPR001155; KEGG: scl:sce8661 oxidoreductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD dependent oxidoreductase; SPTR: A9G078 Probable oxidoreductase; PFAM: FAD binding domain; NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.415
Krac_3303
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003594:IPR009082:IPR005467:IPR004358:IPR 003661; KEGG: ttr:Tter_2374 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: D1CHQ0 Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.410
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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