STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krac_4240COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR013815; KEGG: art:Arth_0384 phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: A0JRW5 Phosphoenolpyruvate synthase; manually curated; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (915 aa)    
Predicted Functional Partners:
Krac_9833
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
   
  0.932
Krac_6794
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002869:IPR009014:IPR019752:IPR015941:IPR 002880; KEGG: chl:Chy400_1038 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: B9LLV4 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
    
 0.821
Krac_7768
Biotin/lipoyl attachment domain-containing protein; COGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR011053:IPR000089; KEGG: dau:Daud_1015 pyruvate carboxylase subunit B; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: B1I3L5 Acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Biotin-requiring enzyme; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein.
    
 0.796
Krac_4239
Transcriptional regulator, MarR family; InterPro IPR000835:IPR011991; KEGG: tro:trd_1169 regulatory protein, MarR; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: C4DQS6 Transcriptional regulator; PFAM: MarR family.
       0.773
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.733
tal-2
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.733
tal-3
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.733
EFH89094.1
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR009014:IPR 015941; KEGG: rmr:Rmar_0991 dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain protein; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: D0MHC7 Dehydrogenase E1 component; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketola [...]
    
 0.714
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.659
Krac_6795
COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011896:IPR011766; KEGG: chl:Chy400_1039 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: B9LLV5 Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxi [...]
    
 0.658
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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