STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krac_6927NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR015797:IPR020084:IPR020476:IPR000086; KEGG: stp:Strop_1988 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: A4X6E2 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. (146 aa)    
Predicted Functional Partners:
Krac_6827
Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR008136:IPR001453; KEGG: mta:Moth_0735 competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; SPTR: Q2RKI6 Putative competence-damage inducible protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-ter [...]
    
  0.655
EFH88778.1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: ttr:Tter_0579 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1CEZ1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...]
    
  0.644
Krac_6928
Transcriptional regulator, XRE family; InterProIPR001387:IPR019734:IPR010982:IPR013026:IPR 001440; KEGG: ami:Amir_1281 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; TPR repeat-containing protein; SMART: helix-turn-helix domain protein; Tetratricopeptide repeat; SPTR: C6WRI1 Transcriptional regulator, XRE family; PFAM: Helix-turn-helix; Tetratricopeptide repeat.
    
  0.620
EFH90826.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.619
Krac_0184
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR015797:IPR020476:IPR020084:IPR000086; KEGG: pna:Pnap_0741 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: A1VK82 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
 
 
 0.598
EFH89634.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.598
Krac_0189
Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; InterPro IPR004821:IPR014729:IPR016429; KEGG: mbt:JTY_0218 putative transcriptional regulatory protein; SPTR: Q7U2K1 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN NADR (PROBABLY ASNC-FAMILY); TIGRFAM: cytidyltransferase-related domain protein; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain.
    
 0.595
Krac_3009
Hypothetical protein; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: A6G9I1 Putative uncharacterized protein.
    
 0.595
Krac_6929
InterPro IPR015038:IPR003819; KEGG: ami:Amir_1283 taurine catabolism dioxygenase TauD/TfdA; PFAM: Taurine catabolism dioxygenase TauD/TfdA; SPTR: C6WRI3 Taurine catabolism dioxygenase TauD/TfdA; PFAM: Taurine catabolism dioxygenase TauD, TfdA family.
 
     0.587
Krac_7682
COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR015421:IPR001085:IPR015424; KEGG: sin:YN1551_1249 glycine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: C3NEW0 Serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase.
    
  0.583
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.