node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFH89634.1 | Krac_7152 | Krac_11199 | Krac_7152 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.753 |
EFH89634.1 | Krac_7572 | Krac_11199 | Krac_7572 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG4886 Leucine-rich repeat (LRR) protein; InterPro IPR020474:IPR003591:IPR001611; KEGG: npu:Npun_F6039 Miro domain-containing protein; PFAM: leucine-rich repeat protein; SPTR: B2IUT6 Miro domain protein; PFAM: Leucine Rich Repeat. | 0.446 |
EFH89634.1 | Krac_7841 | Krac_11199 | Krac_7841 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726:IPR003171; KEGG: tro:trd_1049 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: B9L045 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | 0.999 |
EFH90024.1 | Krac_7152 | Krac_11621 | Krac_7152 | KEGG: chl:Chy400_2442 hypothetical protein; SPTR: B9LIP2 Putative uncharacterized protein; PFAM: CRISPR-associated protein (Cas_csx3); TIGRFAM: CRISPR-associated protein, Csx3 family. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.628 |
EFH90024.1 | Krac_7841 | Krac_11621 | Krac_7841 | KEGG: chl:Chy400_2442 hypothetical protein; SPTR: B9LIP2 Putative uncharacterized protein; PFAM: CRISPR-associated protein (Cas_csx3); TIGRFAM: CRISPR-associated protein, Csx3 family. | Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726:IPR003171; KEGG: tro:trd_1049 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: B9L045 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | 0.405 |
EFH90188.1 | Krac_7152 | Krac_11798 | Krac_7152 | Clp domain protein; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR004176:IPR001915; KEGG: det:DET1423 M48 family peptidase; PFAM: Clp domain protein; peptidase M48 Ste24p; SPTR: Q3Z6L8 Peptidase, M48 family; PFAM: Peptidase family M48; Clp amino terminal domain. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.529 |
EFH90578.1 | Krac_7152 | Krac_12203 | Krac_7152 | Ste24 endopeptidase; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: aba:Acid345_0572 STE24 endopeptidase; PFAM: peptidase M48 Ste24p; PRIAM: Ste24 endopeptidase; SPTR: Q1IU73 Ste24 endopeptidase; PFAM: Peptidase family M48. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.529 |
Krac_0603 | Krac_7152 | Krac_0603 | Krac_7152 | InterPro IPR005180; KEGG: rlg:Rleg_0019 hypothetical protein; SPTR: C6AYA7 Putative uncharacterized protein; PFAM: Domain of unknown function DUF302. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.584 |
Krac_3595 | Krac_7152 | Krac_3595 | Krac_7152 | InterPro IPR005180; KEGG: sus:Acid_3683 hypothetical protein; SPTR: Q020J8 Putative uncharacterized protein; PFAM: Domain of unknown function DUF302. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.591 |
Krac_3903 | Krac_5312 | Krac_3903 | Krac_5312 | KEGG: cai:Caci_1468 hypothetical protein; SPTR: C7Q9Z3 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | Hypothetical protein; InterPro IPR004378; KEGG: xce:Xcel_1326 hypothetical protein; SPTR: D1BRA2 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | 0.485 |
Krac_3903 | Krac_7152 | Krac_3903 | Krac_7152 | KEGG: cai:Caci_1468 hypothetical protein; SPTR: C7Q9Z3 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.510 |
Krac_5312 | Krac_3903 | Krac_5312 | Krac_3903 | Hypothetical protein; InterPro IPR004378; KEGG: xce:Xcel_1326 hypothetical protein; SPTR: D1BRA2 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | KEGG: cai:Caci_1468 hypothetical protein; SPTR: C7Q9Z3 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | 0.485 |
Krac_5312 | Krac_7152 | Krac_5312 | Krac_7152 | Hypothetical protein; InterPro IPR004378; KEGG: xce:Xcel_1326 hypothetical protein; SPTR: D1BRA2 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | 0.509 |
Krac_7152 | EFH89634.1 | Krac_7152 | Krac_11199 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.753 |
Krac_7152 | EFH90024.1 | Krac_7152 | Krac_11621 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | KEGG: chl:Chy400_2442 hypothetical protein; SPTR: B9LIP2 Putative uncharacterized protein; PFAM: CRISPR-associated protein (Cas_csx3); TIGRFAM: CRISPR-associated protein, Csx3 family. | 0.628 |
Krac_7152 | EFH90188.1 | Krac_7152 | Krac_11798 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | Clp domain protein; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR004176:IPR001915; KEGG: det:DET1423 M48 family peptidase; PFAM: Clp domain protein; peptidase M48 Ste24p; SPTR: Q3Z6L8 Peptidase, M48 family; PFAM: Peptidase family M48; Clp amino terminal domain. | 0.529 |
Krac_7152 | EFH90578.1 | Krac_7152 | Krac_12203 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | Ste24 endopeptidase; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: aba:Acid345_0572 STE24 endopeptidase; PFAM: peptidase M48 Ste24p; PRIAM: Ste24 endopeptidase; SPTR: Q1IU73 Ste24 endopeptidase; PFAM: Peptidase family M48. | 0.529 |
Krac_7152 | Krac_0603 | Krac_7152 | Krac_0603 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | InterPro IPR005180; KEGG: rlg:Rleg_0019 hypothetical protein; SPTR: C6AYA7 Putative uncharacterized protein; PFAM: Domain of unknown function DUF302. | 0.584 |
Krac_7152 | Krac_3595 | Krac_7152 | Krac_3595 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | InterPro IPR005180; KEGG: sus:Acid_3683 hypothetical protein; SPTR: Q020J8 Putative uncharacterized protein; PFAM: Domain of unknown function DUF302. | 0.591 |
Krac_7152 | Krac_3903 | Krac_7152 | Krac_3903 | COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; InterPro IPR007269; KEGG: mmi:MMAR_4222 integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: B2HS52 Conserved integral membrane protein; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family. | KEGG: cai:Caci_1468 hypothetical protein; SPTR: C7Q9Z3 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026. | 0.510 |