STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (223 aa)    
Predicted Functional Partners:
Krac_8705
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.990
Krac_7556
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019575:IPR001949; KEGG: swo:Swol_0657 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: B2BSJ8 NADPH-dependent sulfur oxidoreductase B subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit.
  
   0.981
EFH88919.1
Amino acid adenylation domain protein; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR006162:IPR020845:IPR001242:IPR 000873:IPR006163:IPR009081:IPR020459; KEGG: npu:Npun_F2181 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; SPTR: Q9RAH1 NosD; TIGRFAM: amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain.
  
 
 0.979
EFH90118.1
COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR016038:IPR001227:IPR000873:IPR006163:IPR 014030:IPR014031:IPR014043:IPR016039:IPR016035:IPR009081:I PR016036:IPR006162:IPR020845:IPR018201; KEGG: ava:Ava_4108 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; AMP-dependent synthetase and ligase; phosphopantetheine-binding; Acyl transferase; SPTR: Q3M5M8 Beta-ketoacyl synthase; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain.
  
 
 0.979
Krac_6972
Amino acid adenylation domain protein; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR009081:IPR006162:IPR020845:IPR 001242:IPR000873:IPR006163:IPR001031; KEGG: ava:Ava_1611 amino acid adenylation; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Thioesterase; SPTR: Q3MCQ2 Amino acid adenylation; TIGRFAM: amino acid adenylation domain protein; PFAM: Thioesterase domain; Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain.
  
 
 0.977
EFH89020.1
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.897
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
   
 0.874
EFH90488.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR000873; KEGG: gbm:Gbem_2216 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B5EE83 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
  
 
 0.810
Krac_6665
COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941:IPR017909:IPR005805:IPR006311; KEGG: hau:Haur_4253 Rieske (2Fe-2S) domain-containing protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: A9AXG5 Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] domain.
    
   0.792
Krac_8626
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
   0.792
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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