STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krac_8690PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR002054:IPR003583:IPR003141:IPR002008:IPR 016195:IPR010996:IPR010994:IPR004013; KEGG: pmo:Pmob_0486 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: A9BFQ2 PHP domain protein; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family. (589 aa)    
Predicted Functional Partners:
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 0.933
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.912
Krac_8352
Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: tbd:Tbd_1473 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: C1WG24 Metal-dependent hydrolase; PFAM: Endonuclease/Exonuclease/phosphatase family.
   
 0.886
Krac_9623
COGs: COG0258 5'-3' exonuclease (including N-terminal domain of PolI); InterProIPR020045:IPR020046:IPR020047:IPR002421:IPR 008918; KEGG: hoh:Hoch_5169 5'-3' exonuclease, SAM-fold domain protein; PFAM: 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; SPTR: D0LWK7 5'-3' exonuclease, SAM-fold domain protein; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain.
  
 0.879
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.818
Krac_5087
RNA-metabolising metallo-beta-lactamase; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: hau:Haur_5264 beta-lactamase domain-containing protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: A9B977 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.
    
 0.801
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.773
Krac_2074
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR015421:IPR015422:IPR004838:IPR004839:IPR 015424; KEGG: rxy:Rxyl_0650 L-threonine O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Q1AYA8 L-threonine O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase.
  
 
 0.770
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR004839:IPR005861:IPR015424:IPR015421:IPR 015422; KEGG: chl:Chy400_2086 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: B9LFY5 Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.767
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
 
 0.686
Your Current Organism:
Ktedonobacter racemifer
NCBI taxonomy Id: 485913
Other names: K. racemifer DSM 44963, Ktedonobacter racemifer DSM 44963, Ktedonobacter racemifer str. DSM 44963, Ktedonobacter racemifer strain DSM 44963
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