STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1373 aa)    
Predicted Functional Partners:
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
 
 
 0.975
pcn
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 
 
 0.885
Hmuk_0764
PFAM: protein of unknown function DUF296; KEGG: hma:rrnAC2689 hypothetical protein.
       0.862
Hmuk_0815
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
 
   
 0.736
nac
alpha-NAC related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.734
Hmuk_2882
PFAM: protein of unknown function DUF75; KEGG: hma:rrnAC3510 hypothetical protein.
  
     0.708
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.705
Hmuk_1059
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: hma:rrnAC3094 RecJ-like exonuclease.
 
     0.703
rpl31e
PFAM: Ribosomal protein L31e; KEGG: hma:rrnAC3113 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
     0.671
Hmuk_2672
PFAM: Protein of unknown function DUF655; KEGG: hma:rrnAC0258 hypothetical protein.
  
     0.666
Your Current Organism:
Halomicrobium mukohataei
NCBI taxonomy Id: 485914
Other names: H. mukohataei DSM 12286, Halomicrobium mukohataei DSM 12286, Halomicrobium mukohataei str. DSM 12286, Halomicrobium mukohataei strain DSM 12286
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.