STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (268 aa)    
Predicted Functional Partners:
Hmuk_1100
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
 0.996
ilvD
KEGG: hma:rrnAC0302 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
    
 0.947
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.923
Hmuk_2928
PFAM: aminotransferase class IV; KEGG: hma:rrnAC0711 branched-chain amino acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.923
Hmuk_1495
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
      0.798
Hmuk_2856
TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; KEGG: hma:rrnAC3539 pantothenate metabolism flavoprotein.
 
   
 0.768
Hmuk_2084
KEGG: nph:NP4336A hypothetical protein.
       0.708
Hmuk_2576
KEGG: hma:rrnAC0001 biotin-(acetyl-CoA carboxylase) ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; Helix-turn-helix type 11 domain protein.
  
  
 0.607
Hmuk_1541
PFAM: Na+/solute symporter; KEGG: hma:rrnAC1726 pantothenate permease; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.568
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.567
Your Current Organism:
Halomicrobium mukohataei
NCBI taxonomy Id: 485914
Other names: H. mukohataei DSM 12286, Halomicrobium mukohataei DSM 12286, Halomicrobium mukohataei str. DSM 12286, Halomicrobium mukohataei strain DSM 12286
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