STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dret_0729PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: dvm:DvMF_0798 thiamine biosynthesis protein ThiF. (219 aa)    
Predicted Functional Partners:
Dret_0726
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mxa:MXAN_3269 thiamine biosynthesis protein ThiS.
 
 0.992
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.966
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.935
Dret_0728
TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: dde:Dde_1556 thiamine biosynthesis protein ThiH.
 
  
 0.921
Dret_2093
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: dal:Dalk_1983 UBA/ThiF-type NAD/FAD binding protein.
  
     0.764
Dret_2318
PFAM: thiamineS protein; KEGG: gme:Gmet_1044 thiamine S.
  
 
 0.758
Dret_0173
PFAM: thiamineS protein; KEGG: dma:DMR_26290 hypothetical protein.
  
 
 0.743
Dret_1740
KEGG: dvm:DvMF_0872 hypothetical protein.
  
 0.700
Dret_1362
KEGG: dma:DMR_30610 hypothetical protein.
  
 
 0.675
Dret_0100
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
   
 0.651
Your Current Organism:
Desulfohalobium retbaense
NCBI taxonomy Id: 485915
Other names: D. retbaense DSM 5692, Desulfohalobium retbaense DSM 5692, Desulfohalobium retbaense str. DSM 5692, Desulfohalobium retbaense strain DSM 5692
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