STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.999
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.990
Dret_0438
PFAM: Asparaginase/glutaminase; KEGG: ank:AnaeK_1739 asparaginase.
     
 0.847
Dret_1373
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.829
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
  
 0.814
Dret_2167
TIGRFAM: aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; KEGG: dvm:DvMF_0565 aspartate ammonia-lyase.
     
 0.814
Dret_0079
PFAM: aminotransferase class I and II; KEGG: dvm:DvMF_2204 aminotransferase class I and II.
    
 0.811
Dret_2027
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: dvl:Dvul_2140 aspartate aminotransferase.
    
 0.811
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.808
argG
KEGG: dde:Dde_2531 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.800
Your Current Organism:
Desulfohalobium retbaense
NCBI taxonomy Id: 485915
Other names: D. retbaense DSM 5692, Desulfohalobium retbaense DSM 5692, Desulfohalobium retbaense str. DSM 5692, Desulfohalobium retbaense strain DSM 5692
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