Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Dret_1069TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: dvl:Dvul_0124 tartrate/fumarate subfamily Fe- S type hydro-lyase beta subunit. (184 aa)    
Predicted Functional Partners:
Dret_1068
KEGG: dvm:DvMF_2461 fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
 0.999
Dret_1067
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: dma:DMR_05780 fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.996
Dret_0778
Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: dde:Dde_1253 malate dehydrogenase.
 
 
 0.992
Dret_1066
KEGG: dde:Dde_1257 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 
 0.989
Dret_1065
PFAM: Fumarate reductase respiratory complex; KEGG: dde:Dde_1258 fumarate reductase, cytochrome b subunit.
  
 
 0.982
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.909
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.857
Dret_0439
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: dvu:DVU0477 isocitrate dehydrogenase, NADP- dependent.
  
  
 0.844
Dret_2307
TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: dma:DMR_17530 succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.814
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_2530 argininosuccinate lyase.
    
 0.813
Your Current Organism:
Desulfohalobium retbaense
NCBI taxonomy Id: 485915
Other names: D. retbaense DSM 5692, Desulfohalobium retbaense DSM 5692, Desulfohalobium retbaense str. DSM 5692, Desulfohalobium retbaense strain DSM 5692
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