STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dret_1396KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. (1159 aa)    
Predicted Functional Partners:
Dret_1427
PFAM: DNA polymerase III delta; KEGG: dma:DMR_44680 hypothetical protein.
  
 0.991
Dret_2471
KEGG: dde:Dde_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain.
    
 0.990
Dret_2477
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: dde:Dde_0628 DNA polymerase III, epsilon subunit.
   
 0.990
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.980
Dret_2290
KEGG: dde:Dde_0177 DNA polymerase III, delta prime subunit, putative.
 
 0.980
Dret_1124
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: dds:Ddes_0455 single-strand binding protein.
 
 
 
 0.904
Dret_1614
Hypothetical protein; KEGG: pne:Pnec_1608 single-strand binding protein.
   
 
 0.769
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.701
Dret_1395
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dvl:Dvul_1716 putative 6-pyruvoyl tetrahydropterin synthase.
       0.632
Dret_1394
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality.
       0.609
Your Current Organism:
Desulfohalobium retbaense
NCBI taxonomy Id: 485915
Other names: D. retbaense DSM 5692, Desulfohalobium retbaense DSM 5692, Desulfohalobium retbaense str. DSM 5692, Desulfohalobium retbaense strain DSM 5692
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