STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dret_1957KEGG: dma:DMR_38890 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)    
Predicted Functional Partners:
Dret_0851
TIGRFAM: transketolase; PFAM: Transketolase central region; Transketolase domain protein; KEGG: dma:DMR_21080 transketolase; Belongs to the transketolase family.
 0.996
Dret_1750
PFAM: Transketolase domain protein; Transketolase central region; KEGG: MGC69114; transketolase; K00615 transketolase.
 
 0.951
Dret_0852
KEGG: dvm:DvMF_0481 sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: ribose 5-phosphate isomerase B; sugar- phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase.
 
 
 0.945
Dret_2486
TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: dma:DMR_05560 putative 6-phosphogluconate dehydrogenase.
     
 0.905
Dret_1956
SMART: Transcription regulator, AsnC-type; KEGG: dde:Dde_2578 AsnC family transcriptional regulator.
  
    0.792
Dret_0634
TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; KEGG: gur:Gura_4093 flagellar protein FliS.
    
   0.679
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.638
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
 
 
 0.600
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 
 0.596
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.579
Your Current Organism:
Desulfohalobium retbaense
NCBI taxonomy Id: 485915
Other names: D. retbaense DSM 5692, Desulfohalobium retbaense DSM 5692, Desulfohalobium retbaense str. DSM 5692, Desulfohalobium retbaense strain DSM 5692
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