STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dret_2346PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat protein; KEGG: hypothetical protein. (512 aa)    
Predicted Functional Partners:
Dret_1677
PFAM: beta-lactamase domain protein; RNA- metabolising metallo-beta-lactamase; KEGG: sat:SYN_00166 metallo-beta-lactamase protein.
    
 0.818
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.786
Dret_1158
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat; KEGG: sat:SYN_01501 TPR repeat-containing protein.
  
 0.719
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.654
Dret_0130
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
    
 0.647
Dret_0856
PFAM: Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; TPR repeat-containing protein; SMART: Tetratricopeptide repeat; KEGG: dvm:DvMF_0478 tetratricopeptide TPR_2 repeat protein.
  
 0.642
Dret_0600
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: pca:Pcar_1151 putative anti-sigma-28 factor FlgM.
  
 
 0.638
Dret_0223
PFAM: histone deacetylase superfamily; KEGG: dde:Dde_2337 histone deacetylase family protein.
    
 0.600
Dret_0283
PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dvm:DvMF_0789 non-specific serine/threonine protein kinase.
 
 
 0.586
Dret_2349
SMART: PDZ/DHR/GLGF domain protein; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease.
  
 
  0.579
Your Current Organism:
Desulfohalobium retbaense
NCBI taxonomy Id: 485915
Other names: D. retbaense DSM 5692, Desulfohalobium retbaense DSM 5692, Desulfohalobium retbaense str. DSM 5692, Desulfohalobium retbaense strain DSM 5692
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