STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_0226PFAM: Ppx/GppA phosphatase; KEGG: mxa:MXAN_5759 phosphatase, Ppx/GppA family. (326 aa)    
Predicted Functional Partners:
Dtox_2287
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.923
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
    0.905
Dtox_0225
PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: bsu:BSU00630 hypothetical protein.
       0.835
Dtox_0227
KEGG: bar:GBAA0061 stage II sporulation protein E; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
       0.807
Dtox_0224
PFAM: Septum formation initiator; KEGG: bha:BH0076 cell-division initiation protein (septum formation).
  
  
 0.656
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.504
Dtox_0223
TIGRFAM: spore cortex biosynthesis protein YabQ; KEGG: bar:GBAA0058 hypothetical protein.
       0.488
Dtox_0222
TIGRFAM: sporulation protein YabP; PFAM: YabP family protein; KEGG: bha:BH0074 hypothetical protein.
       0.467
Dtox_2087
PFAM: Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; CBS domain-containing protein; phosphoesterase RecJ domain protein; SMART: CBS domain-containing protein; KEGG: gur:Gura_2246 CBS domain-containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.434
Dtox_0220
PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: bha:BH0073 hypothetical protein.
       0.414
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.