STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_0227KEGG: bar:GBAA0061 stage II sporulation protein E; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (851 aa)    
Predicted Functional Partners:
Dtox_1065
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.950
Dtox_1068
TIGRFAM: stage II sporulation protein R; KEGG: bsu:BSU36970 required for processing of pro- sigma-E.
  
   
 0.877
Dtox_1067
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.867
Dtox_2064
TIGRFAM: anti-sigma F factor antagonist; anti-anti- sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: bsu:BSU23470 anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family.
  
  
 0.857
Dtox_2611
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: bha:BH2797 mutants block sporulation after engulfment.
  
   
 0.838
Dtox_4159
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: bha:BH3740 transcriptional regulator of sigma- E- and sigma-K-dependent.
  
   
 0.830
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.828
Dtox_2111
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.824
Dtox_2469
KEGG: baa:BA_0374 hypothetical protein.
  
   
 0.819
Dtox_0226
PFAM: Ppx/GppA phosphatase; KEGG: mxa:MXAN_5759 phosphatase, Ppx/GppA family.
       0.807
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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