node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtox_3932 | Dtox_4367 | Dtox_3932 | Dtox_4367 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | 0.980 |
Dtox_3932 | ffh | Dtox_3932 | Dtox_1196 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.971 |
Dtox_3932 | ftsY | Dtox_3932 | Dtox_1184 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.977 |
Dtox_3932 | rplA | Dtox_3932 | Dtox_0275 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.714 |
Dtox_3932 | rplJ | Dtox_3932 | Dtox_0276 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.653 |
Dtox_3932 | rplK | Dtox_3932 | Dtox_0274 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.724 |
Dtox_3932 | rpmG | Dtox_3932 | Dtox_0271 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: gsu:GSU2870 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.736 |
Dtox_3932 | secA | Dtox_3932 | Dtox_3971 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.983 |
Dtox_3932 | secE | Dtox_3932 | Dtox_0272 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.997 |
Dtox_3932 | secY | Dtox_3932 | Dtox_0306 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.992 |
Dtox_4367 | Dtox_3932 | Dtox_4367 | Dtox_3932 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.980 |
Dtox_4367 | ffh | Dtox_4367 | Dtox_1196 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.946 |
Dtox_4367 | ftsY | Dtox_4367 | Dtox_1184 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.936 |
Dtox_4367 | rplA | Dtox_4367 | Dtox_0275 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.443 |
Dtox_4367 | rplK | Dtox_4367 | Dtox_0274 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.436 |
Dtox_4367 | rpmG | Dtox_4367 | Dtox_0271 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: gsu:GSU2870 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.541 |
Dtox_4367 | secA | Dtox_4367 | Dtox_3971 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.957 |
Dtox_4367 | secE | Dtox_4367 | Dtox_0272 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.970 |
Dtox_4367 | secY | Dtox_4367 | Dtox_0306 | PFAM: 60 kDa inner membrane insertion protein; KEGG: cco:CCC13826_1623 putative inner membrane protein translocase component YidC. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.985 |
ffh | Dtox_3932 | Dtox_1196 | Dtox_3932 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.971 |