STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_0652PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: bha:BH3863 methyl-accepting chemotaxis protein. (520 aa)    
Predicted Functional Partners:
Dtox_0066
PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: bha:BH2262 modulation of CheA activity in response to attractants (chemotaxis protein).
 
 0.988
Dtox_0655
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; P2 response regulator binding domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; Hpt domain protein; ATP- binding region ATPase domain protein; KEGG: bha:BH2970 two-component sensor histidine kinase involved in chemotaxis.
 
 0.984
Dtox_0611
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; KEGG: pca:Pcar_1197 chemotaxis protein histidine kinase.
 
 0.977
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.976
Dtox_0612
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: dal:Dalk_3928 CheW protein.
 
  0.974
Dtox_3073
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: glo:Glov_2813 CheW protein.
 
  0.974
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  0.955
Dtox_0661
PFAM: CheB methylesterase; KEGG: bav:BAV1679 chemotaxis response regulator protein-glutamate methylesterase.
 
  0.931
Dtox_0614
KEGG: dal:Dalk_3925 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
 
  0.930
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  0.930
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
Server load: medium (52%) [HD]