STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_0767KEGG: tgr:Tgr7_1990 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain-containing protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain-containing protein; PAC repeat-containing protein; PAS domain-containing protein. (1278 aa)    
Predicted Functional Partners:
Dtox_1576
KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein.
 
 
 0.998
Dtox_1555
KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein.
 
 
 0.996
Dtox_0616
KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein.
 
 
 0.983
Dtox_3783
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase.
 
 0.978
Dtox_1676
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain-containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain-containing protein; PAC repeat-containing protein; PAS domain-containing protein.
 
 
0.974
Dtox_0047
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain-containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain-containing protein; PAC repeat-containing protein; PAS domain-containing protein.
 
 
0.972
Dtox_3786
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; KEGG: vvu:VV2_0376 signal transduction histidine kinase.
  
 
 0.969
Dtox_4328
Multi-sensor signal transduction histidine kinase; KEGG: bsu:BSU13530 two-component sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; ATP-binding region ATPase domain protein.
 
 
 0.969
Dtox_1723
KEGG: dat:HRM2_43250 sensory box histidine kinase/response regulator; PFAM: response regulator receiver; Hpt domain protein; SMART: response regulator receiver.
 
 0.966
Dtox_1918
Multi-sensor signal transduction histidine kinase; KEGG: bsu:BSU13530 two-component sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein.
 
 
 0.931
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.