STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_1072Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (162 aa)    
Predicted Functional Partners:
Dtox_1071
KEGG: cla:Cla_0048 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; SMART: Hedgehog/intein hint domain protein.
 
 
 0.960
Dtox_3904
Oxygen-sensitive ribonucleoside-triphosphate reductase-like protein; KEGG: ilo:IL0188 anaerobic ribonucleoside triphosphate reductase.
 
 
 0.832
Dtox_1878
Oxygen-sensitive ribonucleoside-triphosphate reductase-like protein; KEGG: cps:CPS_0092 anaerobic ribonucleoside triphosphate reductase.
 
 
 0.831
Dtox_3631
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aca:ACP_2697 putative 6-pyruvoyl tetrahydropterin synthase.
  
  
 0.769
Dtox_1709
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: bar:GBAA4599 bifunctional acetaldehyde- CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
   
 0.680
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
  
  
 0.654
Dtox_1073
PFAM: Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: bbr:BB3018 putative peptidase.
 
     0.600
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.587
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.523
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
     
 0.407
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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