STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_1175PFAM: regulatory protein DeoR; KEGG: bha:BH2494 fatty acid biosynthesis transcriptional regulator. (197 aa)    
Predicted Functional Partners:
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.967
Dtox_1179
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: bha:BH2492 acyl-carrier-protein S- malonyltransferase.
 
  
 0.915
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.896
Dtox_1180
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.737
Dtox_1178
TIGRFAM: enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase NPD; KEGG: dal:Dalk_5025 2-nitropropane dioxygenase NPD.
       0.734
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.702
rpmF
TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: sfu:Sfum_1369 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
       0.639
codY
GTP-sensing pleiotropic transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
   
 0.612
Dtox_2675
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Non- ribosomal peptide synthetase; phosphopantetheine-binding; condensation domain protein; KEGG: dde:Dde_1609 amino acid adenylation; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.601
Dtox_3744
Putative transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: bha:BH0521 hypothetical protein.
  
     0.595
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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