STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: glo:Glov_3139 glutamate-1-semialdehyde-2,1- aminomutase. (430 aa)    
Predicted Functional Partners:
Dtox_1254
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: glo:Glov_0688 porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.998
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.989
Dtox_1249
TIGRFAM: siroheme synthase; KEGG: sat:SYN_02276 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
   
 0.971
Dtox_1322
6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like.
    
 0.956
Dtox_1252
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dal:Dalk_4009 uroporphyrin-III C- methyltransferase.
 
  
 0.949
Dtox_2675
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Non- ribosomal peptide synthetase; phosphopantetheine-binding; condensation domain protein; KEGG: dde:Dde_1609 amino acid adenylation; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.927
Dtox_1179
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: bha:BH2492 acyl-carrier-protein S- malonyltransferase.
    
 0.916
Dtox_2674
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Methyltransferase type 12; Non-ribosomal peptide synthetase; condensation domain protein; KEGG: pfl:PFL_3492 pyochelin synthetase F.
 
 
 0.868
Dtox_1257
Putative transcriptional regulator, AsnC family; KEGG: dat:HRM2_05170 putative HTH-type transcriptional regulator.
     
 0.785
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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