STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_16395-carboxymethyl-2-hydroxymuconateDelta- isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: dde:Dde_1138 5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase. (251 aa)    
Predicted Functional Partners:
Dtox_1709
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: bar:GBAA4599 bifunctional acetaldehyde- CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.619
Dtox_1341
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: gur:Gura_0655 glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.509
Dtox_1322
6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like.
   
 
 0.499
Dtox_4269
PFAM: Aldehyde Dehydrogenase; KEGG: pap:PSPA7_3909 gamma-glutamyl-gamma- aminobutyraldehyde dehydrogenase (gamma-Glu-gamma- aminobutyraldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.
  
 
 0.496
Dtox_1638
PFAM: glycosyl transferase group 1; KEGG: sus:Acid_4857 glycosyl transferase, group 1.
  
    0.495
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
       0.494
Dtox_0905
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase.
     
 0.479
Dtox_1989
PFAM: Citrate synthase; KEGG: sfu:Sfum_2105 citrate (Si)-synthase; Belongs to the citrate synthase family.
   
    0.442
leuB
3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
    0.418
Dtox_2674
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Methyltransferase type 12; Non-ribosomal peptide synthetase; condensation domain protein; KEGG: pfl:PFL_3492 pyochelin synthetase F.
  
  
 0.405
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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