STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_1679TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: dde:Dde_1554 thiamine biosynthesis protein ThiS. (66 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.999
Dtox_1682
TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: sat:SYN_00438 thiamine biosynthesis protein ThiF.
 
 0.998
Dtox_1681
TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: sat:SYN_00439 thiamine biosynthesis protein ThiH.
 
    0.950
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.944
Dtox_1670
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: dol:Dole_2517 phosphomethylpyrimidine kinase.
  
    0.874
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.783
Dtox_1596
TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; KEGG: glo:Glov_2764 thiamine biosynthesis protein ThiC.
  
  
 0.647
Dtox_1597
TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; KEGG: gme:Gmet_2910 thiamine biosynthesis protein ThiC.
  
  
 0.647
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
   0.623
Dtox_2367
PFAM: PP-loop domain protein; KEGG: ppd:Ppro_3499 PP-loop domain-containing protein; Belongs to the TtcA family.
  
   0.623
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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