STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_1691KEGG: viral A-type inclusion protein. (1493 aa)    
Predicted Functional Partners:
Dtox_1690
Hypothetical protein.
 
     0.961
Dtox_1688
KEGG: dat:HRM2_49130 hypothetical protein.
 
     0.937
Dtox_1689
KEGG: hypothetical protein.
 
     0.937
Dtox_3002
KEGG: cha:CHAB381_0396 CRISPR-associated helicase Cas3 domain-containing protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicase.
  
     0.514
Dtox_2774
PFAM: regulatory protein TetR; KEGG: sus:Acid_6731 TetR family transcriptional regulator.
  
     0.472
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.464
Dtox_0834
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; putative transposase IS891/IS1136/IS1341 family; KEGG: baa:BA_2006 hypothetical protein.
  
     0.443
Dtox_2881
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; putative transposase IS891/IS1136/IS1341 family; KEGG: baa:BA_2006 hypothetical protein.
  
     0.430
Dtox_3384
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; putative transposase IS891/IS1136/IS1341 family; KEGG: baa:BA_2006 hypothetical protein.
  
     0.430
Dtox_2569
KEGG: ecc:c2762 sensory histidine kinase AtoS; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
     0.405
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
Server load: medium (48%) [HD]