STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_1913KEGG: dal:Dalk_1286 PAS modulated sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; CBS domain-containing protein; PAS fold-4 domain protein; PAS fold domain protein; ATPase associated with various cellular activities AAA_5; SMART: CBS domain-containing protein; AAA ATPase; PAS domain-containing protein. (710 aa)    
Predicted Functional Partners:
Dtox_3938
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; KEGG: gsu:GSU1887 RNA polymerase sigma-54 factor.
 
   
 0.866
Dtox_0088
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2957 pyruvate-flavodoxin oxidoreductase.
   
 
 0.714
Dtox_1576
KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein.
     
 0.683
Dtox_1555
KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein.
   
 
 0.631
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.612
Dtox_0767
KEGG: tgr:Tgr7_1990 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain-containing protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain-containing protein; PAC repeat-containing protein; PAS domain-containing protein.
     
 0.607
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.549
Dtox_1709
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: bar:GBAA4599 bifunctional acetaldehyde- CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.545
Dtox_3783
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase.
     
 0.541
Dtox_1316
Putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; KEGG: bha:BH1826 transcriptional activator of the acetoin dehydrogenase operon.
  
     0.538
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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